Multicellular systems, microbial biofilms and most animal tissues, consist of cells embedded in an Extracellular Matrix, a three-dimensional network of extracellular macromolecules such as cell membranes, proteins, DNA and their assemblies that provide structural and biochemical support to surrounding cells.

The Wang Lab at the University of Notre Dame focuses on deciphering multiscale extracellular matrix and interfaces for rational design of Nanotherapeutics and Biomimetic Materials, by converging computational, experimental methods and bio-evaluation platforms, in order to provide insights and to advance material science and biomedical engineering in healthcare and environment.