We are designing therapeutics using engineered nanomaterials, targeting pathological ECM of multicellular system such as biofilm and cancer. It will involve design, synthesis and characterization of nanomaterials such as carbon-based and inorganic nanoparticles, as well as application and evaluation of them in biological systems.
1. Cancer Treatment
Wang, Y.; Bahng, J. H.; Che, Q.; Han, J.; Kotov, N. A. Anomalously Fast Diffusion of Targeted Carbon Nanotubes in Cellular Spheroids. ACS Nano 2015, 9, 8231–8238.
Suzuki, N.; Wang, Y.; Elvati, P.; Qu, Z.-B.; Kim, K.; Jiang, S.; Baumeister, E.; Lee, J.; Yeom, B.; Bahng, J. H.; et al. Chiral Graphene Quantum Dots. ACS Nano 2016, 10, 1744–1755
2. Anti-Bacteria/Biofilm
Wang, Y.;et.al. Anti-Biofilm Activity of Graphene Quantum Dots via Self-Assembly with Bacterial Amyloid Proteins. ACS Nano 2019, 13, 4278–4289.
